Most people will care about
something not in ASCII.
Windows-1252 encoding was supported on American computers long before Unicode. I remember “smart quotes” being promoted as a feature of word processors.
Even for people who didn't care for the quotes:
• everyone appreciates ¢, ° for °F or 46° N, ¼, ½, ¾, × and ÷,
• people handling large texts want §, †, ‡ and maybe ¶,
• businesses want ©, ® and ™,
• scientists and engineers need µ, ±, ², ³, ·.
Web browsers have made it more difficult for the average user to enter these characters, but software like Microsoft Word has supported easy ways to insert many of them automatically.