Sure, but when the astronaut application job posting recently came up, I was super excited. I would leave my technical job in a heartbeat to be an astronaut. But, the qualifications specifically needed specific things. Like, iirc, degrees in hard engineering disciplines. Otherwise it was a clear "No." I would expect them to mention things like really, really needing a hard engineering masters (at least, if not PhD) to even not get weeded out at resume review stage.
Also, I know two astronauts relatively well and they say the same thing when the topic has come up. One took a non traditional approach to being an astronaut, applying many times over years, but still had a hard science advanced degree. It's literally a requirement in the application.
To my chagrin, I will never be an astronaut.