David Sinclair on preprint claiming 54% age reversal in rats | Hacker News Reader

David Sinclair on preprint claiming 54% age reversal in rats

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21 pointsk00b14 comments

https://threadreaderapp.com/thread/1259912928695857152.html

Accidental death is ~50/100k/lifetime. So 0.9995^n = 1/2 is our accidental halflife. That's ~1400 lifetimes, or about 100k years. Someone please check.

_Similarly, young mouse blood rejuvenated the hearts and muscles of old mice._

I don't like where this is going. "Sell your young blood to aging old billionaires!"

Is there a reason why people over a specific net worth should be singled out here, and then somehow used as to imply that anti-aging treatments are a net negative?

What about just "helping older people alleviate the painful symptoms of aging and disease"? Most anti-aging treatments we have are certainly not so expensive that only billionaires can afford them (very few things in life are), and are accessible to middle or upper-middle class individuals, with the eventual goal of being accessible to most or all people.

Absolutely, because I'm making the assumption this will be marketed as a product / service. The initial costs will be quite high, as it's a new service. Rich people will buy the service, market forces will keep the prices high, as the only people who can initially afford it will have means to.

Why will market forces keep prices high? Generally, over time, the opposite occurs.

Many new technologies may start out expensive, but I don't see why we should eschew the entire field just because some people will be able to purchase something before others. Someone has to be first to try things out!

I guess I would ask what you'd prefer as an alternative?

Generally, selling body parts is illegal, this is no different. If people could sell their kidneys they would do it to pay rent. I don't think that kind of system ought to exist.

Stelling blood is not illegal. Stelling hair also isn't. Selling vital organs is. Some people sell plasma multiple times each month.

That is not even questioning all the people that need blood transfusions for medical emergencies. Where would that blood come from?

Isn't that already a thing? Was parodied in Silicon Valley HBO at least.

Yes, Ambrosia was the company but I believe it got shutdown.

https://www.businessinsider.com/young-blood-transfusions-ope...

There are about 2100 billionaires in the world. I’d said the market is much larger than that.

Decades ago I used to sell my plasma when I was in college for a little extra cash. If this actually works, you could probably pay your way through college by donating plasma. I think I did it every week.

I don't know if I like the idea of literally selling my lifeblood to go to college

Not all of it.

Why do you need to go to college so bad?

It's the mechanisms that we are after. Like most things, it's discovred in nature first, then we figure out how to make it.

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