The computer science equivalent of the "type of progress" I would like to see is ZFS.
When ZFS was announced, it blew my mind. The Sun ZFS team showed that traditional RAID had a veritable laundry list of fatal, nigh unfixable flaws. Various forms of silent data corruption caused by things such as reordered writes, partial writes, lost writes, or bit flips, and the like.
Then they showed how Merkle Trees provide a simple, unified, provably correct mathematical model of data integrity that in one fell swoop permanently eliminates all of the issues with traditional RAID data integrity. Poof. Gone! Reordered writes: detected. Lost writes: detected. Bit flips: detected. ZFS could even protect against malware in the drive firmware. RAID has no hope.
They demonstrated that in their testing, they had uncovered bugs in several commercial RAID adapter cards and even the DMA chip of one particular motherboard. These were real problems that really were eating people's data!
Did they have online ZFS pool expand on day 1? No. Defrag? No. Encryption? Nope. In fact, it took over a decade to add all of the various features and niceties that people wanted.
That doesn't matter though, because on Day 1 they demonstrated a fundamentally better way of storing data.
Stephen Wolfram hasn't really done this. To put things in the above terms, he hasn't managed to even store a file and retrieve it intact yet, and there's no firm indication that this will ever be possible. This makes his system indistinguishable from /dev/null.
Worse, his system may be the type where you can put files in, but when you try to read them back out, the filesystem simply contains an infinite list of files, one for all possible bit strings. I mean sure, technically your file is in there... somewhere. But this is indistinguishable from /dev/random. Also not useful.