Furthermore it seems as if mutations to the spike gene unique to hCov-2019 somehow is involved in suppression of immune systems’ ability to properly regulate its inflammation response; specifically, it seems to mess with the correct functioning of “M2” macrophages that act in a wound-healing mode to regulate the activity of proinflammatory “M1” macrophages. This leads to a runaway inflammation response.

The antibodies described here need to be tested en vivo (monkeys perhaps) to make sure they don’t actually lead to worse pathology (which for hCov-2019 seems to be immune mediated rather than directly caused by virus)

See my Twitter feed for references, I’ve been tweeting an immuno lit review (@100ideas).