I took Chloroquine as a prophylactic anti-malarial before and during a trip to Central America. You can get the crazy dreams whether or not you’re infected. Mine were, fortunately, quite vivid (and sometimes lucid) but not disturbing. The scenarios were pretty wild though. Other friends of mine had less pleasant experiences. For example, one had a recurring dream that his abdomen got ripped open, a load of pebbles fell out (instead of viscera), and a flock of ravens came and eat the pebbles while he watched in agony. Every night, over and over, for about two months.

During your waking hours, nothing feels amiss at all. Keep in mind too that the dosing is once a week. It took a week or two for the effects to start for me, and they persisted for almost a month after I was home. Unlike reports from the various psychedelics you listed, I felt absolutely no euphoria or “spiritual awakening” from any of it; I just woke up every morning and thought “wow, that was fucked up!”