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> You can ease the cognitive load by making certain programming structures first-class citizens in the language.

Which, in every s-expression based language I'm aware of, can be achieved using macros.

Isn't that the point - s-expressions aren't good enough so people work around them by writing more conventional languages and parsers (the reader macros) to avoid having to write in them.

I don't think that comment was about reader macros. I don't see reader macros used much, while normal macros are frequently used to create new control structures.

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