This is B.S. I don't believe in categorical statements like this. Life is not a constant. A person may be friendless, powerless, weak and even childless for two decades. But all of that can suddenly change. As for ugly, I've seen the ugliest people marry the most beautiful people. And some of these ugly people were total shy, introverts.
So if you are ugly like me, and if you're down in your life like I've been at times when my startup failed, be patient and continue on with life. It will get better. And for love of all that is holy, stay away from these sorts of nonsense absolutisms.