You mean for a bootable partition? If so, then how to restore it? Can the partition be backed up while the OS on it is booted?
Backup to where? To a file on another disk in the same computer, on another computer, to removable media?
I'm running Windows XP SP3 and finally figured out how to use its NTBACKUP to get a copy of a bootable partition and how to restore it. Lesson: Likely need to practice and then take own, clear notes on the details. I wrote some scripts.
The removable media I've been using is just DVDs, and they top out at about 4 GB per DVD. For 20 GB, 200 GB, 1 TB, etc, 4 GB DVDs are a bummer.
I haven't tried double sided DVDs or BluRay. There is the old 'linear tape open' LTO option with about 1 TB per tape, but the drives, and likely the tapes, are expensive, and I know nothing ahout the software available.
Another option is to get a maybe 2 TB external hard disk connected via USB, but, again, I know nothing about the available software, if can do a 'synchronization', etc.