In my experience, this does work somewhat, but doesn't set up the routes properly[1] and doesn't provide an interface to the networkmanager applet, so you are still left with configuring the profiles in the terminal. There is much left to be desired. Sadly the third-party plugin isn't much better and seems to be discontinued[2].

[1] https://forum.manjaro.org/t/wireguard-with-networkmanager-1-... [2] https://github.com/max-moser/network-manager-wireguard/