Rclone is now very prevalent in my infrastructure. Almost all my websites are updated by a CI job that builds the website from a repo and pushes it up to the hosting server. There's an encrypted Rclone config in the repo and the password for it is a really long randomly generated string that gets saved in the CI as a secret. Rclone with Restic is how most of my servers get backed up, Rclone is how I access my Nextcloud and Google Drive, I have a containerized s3 compatible storage system that actually stores it's data on a Rclone remote (I hope `serve s3` gets implemented soon this setup can be simpler [1]), and much more.
I'm using it so much that I'm running up against the Google Drive API limit even though I'm using my own key.