I know this because I live in a very tick infested area (Ozark Mountains) and very few people who've grown up here in families that have lived here for generations get lyme disease. I don't personally know anyone who has.
Since I was kid in the `60s, and long before that, parents here did "tick checks" every evening. After calling us in mom's would strips us little kids down naked and pick any off they found and demand the older kids do it themselves and it becomes a habit. So does being aware. I mean, I don't ignore it when I think I feel one on me and I'm always aware there might be.
I'm 61 now and I've been bit more times than I can count, but I still make a point to do a tick check every evening.
Check out this video I made a couple years ago. They can get thick here...