So one of the main differences is that spicypass is setup-free. You just pick a master password and go. It achieves this by using symmetric encryption via the libsodium library. A nice side-effect of this is that backups are as simple as copying the .spicypass file to your backup device/server. With asymmetric encryption you have to worry about backing up your private keys in addition to the store file(s).
Another major difference is that it has an idle lock. Even if someone has root access to your machine and you leave it unattended while spicypass is running, they won't be able to see your passwords (assuming there's no keylogger involved).
There's also the minimalist aspect. pass has a lot of features that I personally don't need and consider to be bloat. I designed spicypass to my own personal specs: A very simple notepad-like interface, but secure. I figure I can't be the only one who thinks all the bells and whistles that most password managers have just get in the way.