For example, about 80% of adults in the US are either overweight or obese, with some extremely obese. With that come many issues, e.g. diabetes.
So, are we talking about typical people here, many of whom (us) have some form of health issue, e.g. a 40 year old who is overweight and may have high blood pressure because of it, which is very common? Or are we talking about people we consider truly sick and fragile, e.g. a 82 year old who was hospitalised for a heart attack last year, has vitamin deficiencies in the bloodwork, and smoked for 30 years and survived cancer.