Have you researched which applications have the highest penetration of keyboard usage and why? Afaik most users even on desktop apps (e.g MS office suite) can only retain a handful of shortcuts. What's your strategy to train users to have a fully keyboard based navigation?
Btw did you use any open source library to manage keyboard shortcuts?
Compared to normal shortcuts the commands are easier to remember, because they mostly represent the verb for the action you want to accomplish. Instead of memorizing Ctrl + E or similar for a new article, you type /write or an alias like /new. This way you only have to know what actions are possible, without connecting them to an inconclusive key combination. Most commands will auto-complete after the first two letters, so you are not losing that much time either.
Our frontend is build on Vue.js and the shortcuts are handled by global JS events.