I can provide some context here - from my experimentation, after 10 partial updates the contrast is notably worse, but doing a full screen refresh resets things sufficiently that the screen looks sharp again.

To reduce degradations further, whenever UpNext boots it does a cycle of 10 full screen refreshes - overkill certainly, but I think of this as the “cleaning cycle.” If the screen ever starts to fade, I power cycle it, and it’s fine for a long time.

I’ve been running it continuously like this for 2 years now, and while the screen is a bit less sharp than it was originally, it’s still in good shape - the photos in the article are from this week.