I have been working, since September, on my senior project in Pygame. It isn't fun to work in. The documentation is great, but the community seems dead. Things are not easy in Pygame. Distribution is especially painful, with py2exe and py2app and setuptools. I've had a lot of trouble getting certain sounds to play. I would not recommend it.
Really, go with LOVE2D or Flixel or even Flash if you want to make games in a high level language. Not only that, but if you want to have _fun_ making a game, and not get bogged down in low-level details.
I would not recommend Pygame.