How do you think science work? It's like losing weight and gaining muscle, you have to work hard at it and there is no moment in time where you can say that that's the moment you lost weight or gained muscle. It is all incremental progress.
Still, would be nice to be able to point to some tangible result, such as "knowledge obtained eventually led to developing of better treatment for bone cancer" etc.
Doesn't even have to be that. It would even be interesting to know what has been figured out based on the folding even if it hasn't led to any improvements in medical treatments.