Man, I’m just waiting for AWS load balancers to support HTTP2. Last time I checked they still convert HTTP2 into HTTP1 for downstream endpoints.
(Though with HTTP/3 around the corner, I can't imagine anyone will bother working on HTTP/2 to backends.)
Request pipelining and multiplexing are good enough reasons.
"Just" seems like an understatement here, there's a reason why ELBs and ALBs are popular solutions.