One of the things I would love to see would be a voxel-based fighting game. The rage at the time was for texture-mapped polygon fighting games, but the Jaguar was better at voxels (see phase zero
https://www.youtube.com/watch?v=2OPcFdkj0GU).
TBH I reckon the Atari ST and Amiga could've handled a voxel fighter at a decent clip: https://www.youtube.com/watch?v=CmnZoUxXIQM at about 2:46