Effectively, your model is about to get real world stress tested. Depending on your vertical, or your target market you're going to see out-sized impacts either positive or negative. Either way, set a good runway for cash and stay vigilant.

Personally I think a situation like this is a fantastic exercise and a great time to be building a company. Not that I would wish it on anyone, but these kinds of constraints breed an incredible set of solutions. 2008-2010 created a bunch of interesting companies.