The Luddites weren't mad about the advancement of technology, they didn't destroy looms out of religious or anti-technological ideals. Many of them were skilled loom operators. They were squeezed out of their jobs by the race to the bottom, and they were angry that there wasn't any consideration for the paradigm shift they were experiencing.
If Waymo turns trucking into an automated business (or even just reduces the number of humans needed to haul cargo), we could be in for a similar situation. I wonder what Waymo is doing to help support the existing drivers, regulating how we should care for the many millions of humans this could impact, etc.
I believe automated vehicles will someday be safer and more desirable, but we need to ensure that they aren't also the villains in the disenfranchisement of millions of people.