And people wonder why I think terminal is pretty horrible environment for anything but purely line driven applications. Just the other day my coworker was asking my why on earth do I run gvim instead of vim in terminal; I feel now vindicated. Sure, I haven't hit this issue but I am all the time cognizant of the eldritch horrors that are the terminal emulation layers, which makes me prefer to avoid them. And having tmux sit in the middle doing another emulation layer does definitely not help the feeling.
I just wish there were more almost ncurses like lightweight toolkits that would run natively in graphical environments, because to me they seem pretty rare.