YMMV with amphetamines -- they seem very specific-body-metabolism specific, but you'll always be fighting your body's attempt to move to homeostasis which means it will be very probable that you'll run into tolerance, diminishing returns, side effects, and so on.

As far as sleep deprivation goes: it's fascinating what happens to our brains at night. Studies show that REM sleep prunes and maintains new synapses associated with development and learning[0], but other studies show that this effect might be amplified with sleep deprivation[1]. If intermittent fasting can cause one's body to behave differently in a fasted state, perhaps intermittent sleep deprivation could cause effects that in moderation are not wholly negative? I really don't know, but anecdotally, I've noticed myself able to sometimes get some huge breakthroughs in the late night hours. This has been happening less frequently as I age and become more proficient at a lot of things I do, though.