I don't believe they'll ban it. I do believe they'll increase friction to the point that it becomes a huge pain to use either for anything but prototyping.
While the guidelines are what the word says, vague guidelines with a lot of room for interpretation, they don’t necessarily dictate any details. When you look at it from a more technical point of view, it’s harder to do something nonconforming with Apple’s frameworks than with 3rd party alternatives.
Games are a different thing. They are more like their own operating system within iOS and usually have their own quirks (to make them playful).