Biological stress is not getting enough nutrients, having to deal with bacterial exotoxin/endotoxin [1] (as pneumonia, a hostile microbiome, etc), lack of sunlight (UV light -> Vitamin D; red light refreshes Cytochrome C Oxidase, an enzyme in the mitochondria [0]), consuming artificial sugar and other fake foods, etc...
Emotional stress is related to how a person responds to situations -- to quote the article, "why crappy childhoods make for adult brains that don’t work well". Different people can respond to the same situation in completely different ways... Some people are able to use their "crappy childhood" as motivation to make something of themselves, while others are disabled by their own similar childhood.
The tragedy of our situation is how the medical profession considers Dr. McEwen's work as interesting but doesn't do anything with it.
[0] https://en.wikipedia.org/wiki/Cytochrome_c_oxidase --- this page doesn't talk about the use of certain wavelengths of red/infrared light to refresh the enzyme. search for 'red light therapy', then buy heat lamps if you're interested. My current setup cost around $20.