The unpredictable number is an (of a few) inputs into the generation of the CVV3, which is also based on a dynamic key from the issuer. Key rotation is on the order of weeks to months (depending on issuer). This is the "unique number" per transaction (part of tag 57 https://emvlab.org/emvtags/show/t57/ )
DPAN is only good for card-present transactions, provided CVV3, transaction counters, etc.