Coronavirus: Five Brits in French ski chalet catch virus
bbc.com
bbc.com
Today confirmed cases stand at 34,964, with 725 dead, and the virus spread to nearly 30 countries. I'd highly recommend this interview from a couple days ago with Neil Ferguson, director of the Institute for Disease and Emergency Analytics at Imperial College London's School of Public Health[1]
Some highlights I'll quote, based on his team's modeling of the true situation vs. the necessarily incomplete confirmed cases:
- China: estimated 10% of total cases detected
- International: estimated 25% of total cases detected
- estimated 50,000 new infections per day in China
- Doubling every 5 days
- Onset to death can take up to 20 days (in fact I think we've seen deaths up to 30 days post-infection now)
The NYT today[2] also quotes leading experts that this virus is almost certain to become a pandemic, and no one can with certainty predict the consequences. All of which is just to say, I think it's time to stop the hot takes about how unseriously you're taking the situation. There seems to now be unanimity among global experts, who are taking it very very seriously indeed. The actions of widespread border closures, travel and economic shutdowns and China forcefully quarantining 500 million citizens also ought to suggest that governments are treating this far differently than the flu or in fact any sort of viral outbreak in perhaps modern history.
[1] https://youtu.be/ALQTdCYGISw [2] https://www.nytimes.com/2020/02/02/health/coronavirus-pandem...
This is from the WHO director’s speech on February 4: “Second, we reiterate our call to all countries not to impose restrictions inconsistent with the International Health Regulations.
Such restrictions can have the effect of increasing fear and stigma, with little public health benefit.
So far, 22 countries have reported such restrictions to WHO.
Where such measures have been implemented, we urge that they are short in duration, proportionate to the public health risks, and are reconsidered regularly as the situation evolves.”
https://www.reuters.com/article/us-china-health-who-idUSKBN1...
When the 2009 H1N1 flu virus hit, it infected 11% to 21% of the world's population. The mortality rate was low, at just 0.02%, but because of the number of people it infected it resulted in 284,000 deaths.
When a novel disease hits the population for the first time, it often spreads faster and wider than diseases for which we've developed some immunity.
The coronavirus mortality rate so far is alarmingly high. It is highly uncertain and very preliminary, but it could go in either direction. Early estimates of SARS were that it had a fatality rate of <3%. It was eventually revised upward to 9.6%.
It is still troubling because if you assume the impact is like viral pneumonia then the impact of effectively doubling the number of cases of that worldwide will stress our health care systems, and it will increase mortality in vulnerable populations (very young and older people with comorbidities). I'm a bit worried about my mom and dad who are pushing 80 now, I'm not much worried about myself (48 with no other issues). Healthy 25 year olds probably won't catch this at all, and if they do they'll just get a bad cold.
I believe they only tested ~300 people.
"We report the epidemiological, clinical, laboratory, and radiological characteristics, treatment, and clinical outcomes of 41 laboratory-confirmed cases infected with 2019-nCoV. The median age of patients was 49·0 years (IQR 41·0–58·0), and 13 (32%) patients had underlying disease. All patients had pneumonia. A third of patients were admitted to intensive care units, and six died."
Looking at Fig 1 one-third of patients in the 25-49 age group needed intensive care. Maybe the were all above 40, but anyway I don't think that looks like the usual influenza-related pneumonia.
https://marlin-prod.literatumonline.com/cms/attachment/f86df...
Normally even if it works there'd be months of safety trails but if hundreds are dying daily of the virus it might be worth cutting corners on that perhaps. Especially for high risk groups.
Consider: Many major cities in China already have infected populations in the hundreds or thousands, and growing: https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.h... -- these are official, confirmed figures.
See also https://www.thelancet.com/action/showPdf?pii=S0140-6736%2820... for maximum-likelihood estimates of the size of the outbreak as of month-end.
Agree. It seems to be most like another global strand of flu.
This was posted earlier on HN
Life and Death in a Wuhan Coronavirus ICU - https://www.straitstimes.com/asia/east-asia/reporters-notebo...
The mortality rate will be different depending on the health system, since a significant number of people with this virus require either supplementary oxygen or more seriously ICU care.
If this were to become an epidemic in India for example, a higher mortality rate would be expected. In Africa it could be severely bad due to the large numbers of people with AIDS and the tendency of this virus to suppress the immune system.
There is not a single confirmed case of coronavirus in the entire Central and Eastern Europe, yet[1]. Most likely because there are almost no direct flights from Asia to this region, since it lacks major international metropolitan areas and global tourist attractions.
[1] https://ig.ft.com/autograph/graphics/coronavirus-map.svg
If we are guessing about why (and whether) there is no Coronavirus in CE Europe, “no Chinese” is probably not a good guess.
Consider that Italy has had 3 cases to date: a chinese couple from Wuhan and an italian who was repatriated from Wuhan and is in quarantine.
There are 300k chinese nationals in Italy and about 20k in Hungary, and while I love Budapest the amount of chinese tourists is nothing compared to those in Rome.
https://www.straitstimes.com/asia/east-asia/reporters-notebo...
https://www.thelancet.com/journals/lancet/article/PIIS0140-6...
If this coronavirus becomes an epidemic in a region with poor access to healthcare then we may indeed see mortality rates at or above 10% if people cannot get access to supplemental oxygen.
On the other hand if you get coronavirus now in a country with an advanced healthcare system and have access to an ICU then you have excellent chances to recover.
Since we do not know what countries will be affected in the future we cannot begin to guess what the eventual mortality rate will be.
Analysis of Wuhan Coronavirus Deja Vu: Conclusions http://virological.org/uploads/short-url/z0cOhZzme3C6HtlcOcE...
Maybe the best HN could do, is to help the WHO to get their Corona Virus content right on top of the Google search results. Also something Google could do.
EDIT: Counter point to the infected population in the hundreds of thousands you made in the parent.
EDIT 2: Misread 100s or 1000s for hundreds of thousands. So yeah, official numbers.
Also, one reason people use other than official reports is that some are more often updated or emphasize more interesting details. One that I found good is https://bnonews.com/index.php/2020/02/the-latest-coronavirus... which is the one referenced by the wikipedia page https://en.wikipedia.org/wiki/2019%E2%80%9320_Wuhan_coronavi...
https://www.nytimes.com/2020/02/07/health/cdc-coronavirus-ch...
I do realise that this argument could easily be used as a carte-blanche for making completely baseless claims. But I think the best we can do is use many sources and remain somewhat sceptical of all of them - not necessarily in equal measure.
>Professor Neil Ferguson said coronavirus could be infecting around 50,000 people a day in China.
re the official numbers:
>A steady rate of 3,000 diagnoses per day points to the upper limit of detection kits that are available to the health workers
He runs the MRC Centre for Global Infectious Disease Analysis at Imperial College London - not some random crank https://www.ccn.com/professor-says-coronavirus-infecting-500...
So, if this becomes an insurmountable pandemic, you're right that it may eventually reach a flu-like equilibrium and treatability, but we're talking deaths in the millions until then, unless it can be brought under control before that happens.
The flu in the US kills less than 0.1% of infected. 12,000 - 80,000 people die every year, just in the US. (where nearly half the population gets a flu vaccine every year and there is health infrastructure to treat the worst cases).
The new coronavirus' mortality rate is very unknown, but if it's anywhere close to the 2% number, and it spreads in a similar way to the flu, it could easily cause the deaths of millions of people.
Considering the relatively small size of the country and its high population density I agree that it might be a higher risk that China as a whole.
That might look like more cases compared to countries that either don't care or under-report.
Edit: Okay the 89 number I saw includes 64 cases on a Japanese cruise ship.
Things seems under control in Japan.
I am in Singapore right now, and this is untrue.
The government is just reporting infection cases as they show up, and tracing the patients' contacts to keep them under quarantine.
I suspect that some other countries in the region might have higher actual coronavirus infection numbers, but are reporting the cases as influenza or pneumonia.
Singapore has the highest official numbers of cases outside China apart from Japan (but that's because of their cruise ship situation) and the situation is clearly not under control according to official news report.
The latest report from Singapore is indeed local transmission including a case that had no known contact with other known cases.
Third case in the UK is from someone who visited Singapore.
New cases in France are from someone who visited Singapore.
I'm not trying to make people panic but, reasonably, the same restrictions to travels as China should apply to Singapore at the time being.
> New cases in France are from someone who visited Singapore.
These cases are the same person: a UK person who attended the international Servomex meeting in Singapore, and then holidayed at the France ski chalet: https://www.telegraph.co.uk/news/2020/02/08/coronavirus-holi...
Nor is it clear that this article contradicts what I wrote.
If you say: - The only cases that we will confirm have a positive trst
Then if you only test 3000 today and 4000 tomorrow that would define the curve not the real spread.
Most recent update right now:
上海新增5例新型冠状病毒感染的肺炎确诊病例
Shanghai adds 5 confirmed cases of pneumonia caused by novel coronavirus infection
2020年2月8日0—12时,上海市排除新型冠状病毒感染的肺炎疑似病例11例;新增治愈出院11例;新增确诊病例5例,其中2例为外地来沪人员,3例为本市常住人口。
On 2020-02-08 from 0 to 12, Shanghai handled 11 suspected cases of pneumonia caused by novel coronavirus infection, added 11 cases released from hospital after treatment, added 5 confirmed cases, 2 of which are not originally from Shanghai and 3 are residents.
截至2月8日12时,上海市已累计排除疑似病例877例,发现确诊病例286例。
Until 02-08 at 12 o'clock, Shanghai has already handled a total of 877 suspected cases and discovered 286 confirmed cases.
健康上海12320 Healthy Shanghai 12320
Lots of small spikes can still add up to a smooth curve overall.
Videos from China locals do show way more dead than the official numbers.
Exclusive: Wuhan funeral home staffer reveals real death toll of coronavirus | NTD
https://www.youtube.com/watch?v=-KFxCqV1fPQ
1 funeral home (of many in the city), 11 ovens, running 24/7, 1 body per hour = 260 per day every day max capacity
So those WHO reports are being based of what exactly...oh yeah CCP provided figures.
https://www.nytimes.com/2020/02/07/health/cdc-coronavirus-ch...
I doubt these deaths were counted, nsfw/graphic [2].
Just doing basic research will tell you the Chinese CCP numbers are not accurate.
[1] https://twitter.com/IndoPac_Info/status/1226180829837025281
(Nsfl/ graphic) https://twitter.com/FinnaganMarina/status/122476176399400141...
So what primary source would you recommend?
Now, I am no expert. But when experts in field are indirectly, in the case of China, and directly verify numbers, and these numbers do make sense based on models and expectations, I go with the experts.
And by all respect, these experts are not on Twitter and YouTube. Because all these. Numbers on YouTube and Twitter, all these videos, are impossible to confirm. Impossible to put them in the proper context, location and time vise. And impossible to verify. Add to that the stress and fear of people on the ground producing these videos, and the ignorance of Youtubers not being on the ground, and you get an unreliable, uninformed mess.
Later edit: Add Tianjin and Chengdu to the list [2], which means that out of the 7 biggest Chinese cities only the first 3 are not yet technically on any form of lockdown (Beijing, Shanghai and Chongqing).
Later later edit: Photos + video of people escaping the Shenzen lockdown just before coming into effect yesterday, February 7th [3]
[1] https://www.epochtimes.com/gb/20/2/8/n11853273.htm (Google Translate will help)
[2] https://news.ltn.com.tw/news/world/breakingnews/3061526
[3] https://twitter.com/IndoPac_Info/status/1226130936292499457 and https://twitter.com/freddie1999/status/1225754832751013888
Wearing a mask in public is mandatory. Urban villages have been cordoned off and there are checkpoints to move in and out. Gated communities have also been advised to do temperature checks and record movement. All residents who need to return to work next week are being encouraged to register with the local community center to avoid additional ID checks and bottlenecks at the checkpoint.
Unlike in Hubei, public transport is still running. 外卖 (food delivery) and 快递 (courier services) are still active. Many shops and restaurants are closed, but there are slightly more places open this weekend than there were last weekend.
Our version of the lockdown is still oppressive and inconvenient, but it's looser (or more optimized?) now than it was when it was put into place a week ago. There isn't a sense that people are fleeing the city. On the contrary, they are returning from their home provinces.
Source: I live here.
This site gives you upto date stats. https://wuflu.live
Question:
What do you make of the daily infection rate from China? What does your personal judgement tell you?
That is critical thinking, not refusing to believe primary sources and experts because it is "mainstream" or doesn't confirm your personal opinion.
Also, we already all died from SARS,MERS, H1N1, H1N5, the pig plague in Europe and at least twice from Ebola.
https://www.statnews.com/2020/02/04/two-scenarios-if-new-cor...
It’s still possible that quarantines and travel bans will first halt the outbreak and then eradicate the microbe, and the world will never see 2019-nCoV again, as epidemiologist Dr. Mike Ryan, head of health emergencies at the World Health Organization, told STAT on Saturday. That’s what happened with SARS in 2003.
Many experts, however, view that happy outcome as increasingly unlikely.
08/02/2020 34506 cases 721 fatalities
09/02/2020 38675 cases 808 fatalities
10/02/2020 43084 cases 900 fatalities
11/02/2020 47733 cases 997 fatalities
The 8/2 figures compare with 34 598 and 723 announced on the WHO site or almost spot on. You can check how well they've done with subsequent days here https://www.who.int/emergencies/diseases/novel-coronavirus-2...Given the scenes of chaos on the ground the numbers do seem a little over smooth. You can also pretty much get the fatalities number by dividing the cases by 47.9.
Why aren't people on HN willing to believe official numbers and prediction and model? Because being on HN and tech-savy makes you better at anything, even better than domain experts?
I am worrying as I returned to the UK from Singapore a week ago and now have cold-like symptoms. No coughing, no raised temperature, lungs OK so far... but it's a worry.
(--edit-- actually it looks like one Brit, I had thought the new cases were related to a separate traveller, but it looks like it was the same guy)
Chances are you're fine and will be tested clear, but in the case you are not it would be a disaster to not receive proper treatments / come in to contact with loved ones / come in to contact with the general public.
Which is another reason I think this is just something else that's going around at the moment, that I've picked up since I'm back (I was also only in Singapore for around 12 hours, and didn't encounter many people other than at the airport, though was there for a day or so a week before that). I'll call 111 and see what they say.
I just feel the usual common-cold variety of lousy...
Yes, he was believed to have attended an international business meeting by Servomex: https://www.dailymail.co.uk/health/article-7977725/Britains-...
Latest new case there is not known to have been in contact with any known contaminated person, which is bad news.
Seriously, this breathless "plague!" nonsense absolutely must stop and its purveyors should feel bad for doing so. Bubonic plague has an untreated mortality rate of fifty percent! This, on the other hand, is a nontrivial though increasingly global outbreak of a disease that is unlikely to seriously harm healthy people--CFR rate of mortality seems to be about three percent--and is predominantly a threat to the very young and the elderly.
If this sounds familiar that should be because it maps rather closely to the flu. There are 650,000 deaths per year from the flu--who's suggesting closing the airports over such a Threat To Humanity?
Turn the news off. If you have a brain predisposed to low-information panic it is bad for you.
I feel like we've seen at best mixed information about that. I'm not sure that is the case.
It is certainly worth watching, much as SARS and H1N1 were serious health concerns that needed to be managed at state and international levels. It is not worth John Q. Public panicking about. It is certainly not worth stopping the world over. It is not bubonic effing plague.
There's a lot of mixed information, particularly strange news about cases where folks seem to be recovering and then sort of "relapse" a week or two after it is identified.
The analysis that at least sounds a bit more scientific to me seems to indicate there are a lot of cases where the typically healthy folks are hit hard.
China has seen 804 deaths and 2,374 recoveries the majority of cases still at significant risk. https://en.wikipedia.org/wiki/Timeline_of_the_2019–20_Wuhan_...
The good news is the official rate of new infections has been in steady decline and has finally dropped below 10% per day. Though that may not necessarily be completely accurate either.
Additionally, a lot of people care for the very young and the very old, and they’re not comforted with the sentiment, “well, if you’re healthy you’ll live,”
And I'm going to be frank: the very young and very old could just as easily die of influenza and the people who care for the very young and very old are not, for the most part, even screening for flu shots. I have trouble mustering the emotional energy to care for their fear of the scary black swan when they're standing in a flock of white ones that are themselves dangerous.
No, it is more because SARS was only communicable when the patient was at their worst. This can spread during all phases.
The mortality is lower than SARS but much higher than the flu.
To put it in real terms. If you take the number of people you ever met in your life and gave them a bad flu you might find one who dies. Compare that to taking your mother/father/brothers and immediate families and giving them corona where at least one would die. Compared to SARS where someone in your immediate family would die or ebola where either you or your wife would die.
There is evidence that the study claiming the virus can be transmitted by people without symptoms was flawed.[1]
Also, according to that article, even if asymptomatic people transmit the virus "asymptomatic transmission likely plays a minor role in the epidemic overall, WHO says. People who cough or sneeze are more likely to spread the virus, the agency wrote in a situation report on Saturday."
[1] - https://www.sciencemag.org/news/2020/02/paper-non-symptomati...
I was in this region both during SARS and now. It's very clear from your comments that you weren't really paying attention during SARS and you're misinformed now.
More people have already been infected by this coronavirus than the entire cumulative SARS infections to date. There have been more deaths too, despite its relatively "low" virulence.
> And I'm going to be frank: the very young and very old could just as easily die of influenza
No. This is completely false. Please stop.
A seasonal flu kills 2 per 100k infected and this virus kills ~2,000 per 100k infected. SARS was much more lethal but this is not a garden variety influenza and telling people it is is actively harmful.
The Chinese figures can’t be trusted as the CCP is trying to save face.
Li wenliang died from the virus and was a healthy 33yo.
Honestly all these distractions cut into my Left 4 Dead play time.
>Peng: Based on my observations, a third of patients exhibited inflammation in their whole body. It was not necessarily limited to young adults. The mechanism of a cytokine storm is about whole-body inflammation, which leads to a failure of multiple organs and quickly evolves into the terminal stage. In some fast-progressing cases, it took two to three days to progress from whole-body inflammation to the life-threatening stage.
It is at least noteworthy that Dr Li Wenliang died in his late 30s...
Also the mortality rate seems to be very hard to report on due to compounding issues:
1. Chinese death certificates not recording compounding illnesses as cause of death - making attribution hard.
2. There is a two-three week lag on infected to death but a ~4 day lag on infected detection thus a naive mortality calculation of:
mortality = deaths / infected
Is not going to cut it and is misleading at best.3. There is a mixture of factors making reporting accurately hard: Wuhan health services are at max capacity and everything from detection to care is strained. There is also some mixture of political factors which may mean that numbers coming out of China could be tailored towards some kind of narrative.
I agreed there's a lot of FUD which is probably unnecessary, especially outside of Asia. I think within Asia it is a bit more founded given that population density is so high (just think about things like aircon usage in places like Hong Kong, Singapore and Thailand) AND we've just come out of Chinese New Year which is the largest annual human migration event.
My current read on the situation is that everyone else's fear and overreaction will keep me safe at the very least. I also imagine that there will be a degree of y2k type ignorance revolving around the issue once the dust settles: people on the ground who worked on it will say it was a big fucking deal and crisis was averted through a lot of hard work and coordination. People who were unaffected by it will think it was all a bunch of BS and there was nothing to ever have worried about.
In addition to mortality rate, a highly contagious illness that puts 10-20% of infected in the ICU will quickly overwhelm even the most developed healthcare systems.
“Panic” is never really warranted, but there’s a reason China put their entire economy on lockdown. They have the data that you don’t, and they seem pretty concerned.
Whether we should shut down airports is a discussion worth having, but whether this is a serious global threat has already been well established. Unclear on why you seem determined to ignore the experts, none of whom seem to think this is no big deal.
https://sinopsis.cz/en/an-analysis-of-reported-cases-of-2019...
The deaths are really mostly old people with preexisting conditions there.