Yup, we left SF for pretty much the same reasons:
1) Homeless encampments in our neighborhood, full of garbage, feces, urine, and needles. Increase in car theft, breakins and robbery. Various competing homeless cabals running bicycle chop shops, selling parts for drugs. Mentally ill people banging, screaming, fighting in the middle of the night. Hard to sleep through that. Explosive diarrhea smeared on our front door. That was so fun to clean up. City officials unable or unwilling to address the homeless problem.
2) Hellish commute traffic up and down the Peninsula. 280 used to be awesome. Now just a parking lot, just like 101 and 80.
3) Soaring cost of living because of insufficient housing. Anytime a new development is proposed, people are protesting against it, often the same people who are complaining about the high cost of housing. I saw a building aimed for senior citizens tied up in knots for years because of these protesters, on a site that had an abandoned warehouse with broken windows sitting completely empty.
I do miss being able to walk 10 minutes in any direction and find any type of food and restaurant that I wanted. But I started to feel that I was going to get killed by a mentally ill homeless person on that walk to the restaurant. I'm happy we left.