Einstein had a great quote: "The most incomprehensible thing about the world is that it is comprehensible." Well, turns out, a lot of the world is not comprehensible. And that's what made Einstein irrelevant for the latter part of his life.
Our overestimation of the comprehensibility of the world may very well be some version of the Drunkard's search principle. We are much more likely to know about what's comprehensible than what's not.