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Data science, vision, etc - this is where Python reigns supreme and using C# is really going against the rest of the industry.

Using OpenCV from .NET is painful, but from Python it feels native.

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Yeah, this is basically the boat I'm in. Python dominates. You either write it in Python, or maybe get away with writing it in something else and then wrapping it in Python.

I don't mind Python, but now that I've gotten a taste of ADT's and non-nullable types, writing Python feels like a kludge.

Python (the language) feels more like a less-capable version of JavaScript now - with all of the disadvantages of lacking AOT type-safety (I know static type-checks are now available with 3.6 - but remember that most of the world is still using Python2...).

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