This is nothing to be fooled around with and I am not sure if mainstream articles such as these are helpful.
Bufo (Toad/5Meo-DMT) is extremely strong. You smoke it and you are in. Then you typically just drop out of the experience again. For some people it is blissful - like described in the article - the most common experience people have told me about is more like ego death. This can be a great experience, it can feel like hell; but whatever you feel: Integration is key! If you don’t know how to do that or have somebody experienced around: don’t. Maybe you’ll get lucky (many people do) but you might also feel more lost after than ever before.
Personally I find smoking DMT a little hard on the system. It is very different to ingesting it orally and - at least for me - harder to integrate than drinking e.g. Ayahuasca (NN-DMT and/or 5MeO-DMT admixtures). This is coming from someone with a lot of experience.
Psilocybin in small doses with assistance seem way more appropriate to me for people with depressions or similar.
That being said, if you are experienced, feel ready and feel the call: by all means. As the article says, it can be a life changing experience. You should however be ready for that change. Be safe.