I will be curious what kinds of bugs blocking said requests flushes out of various applications. I expect some applications will be built robustly and gracefully accept that adserver.trackallusers.com has suddenly ceased to exist forever, and continue to do what the user expects them to do. But, I will not be surprised if other applications turn out to crash, turn into security vulnerabilities, or throw up annoying popups that say something like, "We use advertisements to pay for this awesome free service we give you. :( Please unblock evil-cabal.org. An assassin has been dispatched to ensure your compliance." Okay, maybe I'm not expecting that last one quite so much, but crashes and breakages are totally plausible, IMO.