There is some truth in the Buddhist truth of "Dukkha" (that life is suffering).
Most of us are simply seeking ways to enjoy the ride and have a meaningful existence while we're here. Some people try mind-altering substances in small doses to explore different states of existence, cope with pain, celebrate, meditate, etc.
We all do things to numb our pain don't we? Medication, activities, work, family, hobbies, art, music, whatever.
I believe legalizing psychedelics will give us a chance to better study and understand what precautions we need to give to people curious.