Someone knowledgeable please advise:
Do cryotherapy or cold showers increase the risk of developing Alzheimer's disease in the long term?
"Tau phosphorylation is exquisitely sensitive to temperature, increasing by 80% for each degree below 37°C, due to exponential decrease in PP2A activity during direct hypothermia, or anesthesia-induced hypothermia."
This means that one might expect a significant increase in tau phosphorylation from modest decreases in body temperature, possibly leading to increased risk of Alzheimer's in the long run.