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In short, some software (Adobe included) makes use of features that are available on Intel processors but not on AMD. Whilst both AMD and Intel are x86-64 they do both have their own unique features. For example, on Intel you've got fast memset, which doesn't exist on AMD.

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But Adobe apps run on Windows with AMD, which means they custom build/compile their apps for each OS ( which is perfectly normal ) and since Apple only deals with Intel CPU's it's understandable.

Maybe it would be better to check for CPU capabilities at runtime and have a more portable app, but what do I know, obviously Adobe PMs will not pay the cost just so some mutts can run hackintosh.

My understanding is it's actually a limitation of the Intel C++ compiler they use but I can't confirm this. On Windows it bakes in some conditionals to check if the CPU is GenuineIntel before doing some things, on macOS it doesn't bother.

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