Drives for the wrong region? What is that?
It's worth doing a warranty check with the manufacturer as soon as you receive the drive if there's any possibility at all it might not be up and up, so that you have an opportunity to return the drive if you want to.
Even if the drive is legitimate, a vendor might sell you an OEM drive which means having to go through that vendor for warranty service instead of direct with the manufacturer. That might be too much of a hassle.
DVD/BluRay implement a lot of the distribution layer of segmentation in hardware and software, but the notion exists in lots of goods, such as in the marketing of high-end watches to different countries.