> As far as ad blocking is concerned, this is less of a restriction than it may seem, since ad sources are often identifiable by the host name
Except if you use YouTube, which is a pretty significant service but impossible to use domain-based adblock like pi-hole with since both ads and content are served through the same Google domain. If you use the YouTube for Android app that means you have to sit through ads.
The alternative is something like invidious[0], but last time I tried it was impossible to seek videos more than half an hour because the seek bar shares its space with the player controls so it ends up occupying only ~15% of the viewport. That or waiting for Firefox Nightly to support WebExtensions.