Women on hormonal contraceptives have reduced perseverance on cognitive tasks
psypost.org
psypost.org
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Unfortunately it’s 2020 and I can imagine too well how seriously these women’s reports of “side reactions” were taken.
[1] Pincus, Garcia, Rock (1959): Effectiveness of an oral contraceptive.
What's important is that the side-effects are known by the individuals that take the medicine.
Alternative solutions that don’t involve selling pills for years are underexplored to the point that research is actively prohibited (e.g. psychedelics against addictions or depression).