a) there are sites that will compare cost of living between places, so thats probably worth looking up

b) How does the rest of your family feel? Uprooting a family is never a particularly pleasant experience, but there are better and worse times/situations.

c) Why do you want to work there? Is it for the prestige? Is it because you'll get to work on something you really enjoy? Not saying theres any wrong/right answers, but at the least its a worthwhile thought exercise.