My Father-in-law had a house built a couple years ago. The guy that did the A/V used the same setup you are talking about (Denon A/V receiver, multi-zone audio for whole house music, IR blaster for A/V system in a cabinet in the next room, 5+1 surround).
They struggle with that system. It required a dedicated smart remote to turn on and control all the gear. But instead of a Logitech Harmony, he used some other brand that "is easier for installers to program". I had to make YouTube videos to remind myself and my FIL how to operate the system, particularly for less used configurations like playing a DVD or playing music on the deck...
I was pretty shocked, because this was basically the A/V setup I had 20 years ago...
My current setup is: Everything goes to the TV (PS4, Chromecast, soundbar), Soundbar is controlled by the TV remote using CEC (Consumer Electronics Control). Most things are controllable by the TV remote.
CEC allows the TV to tell the soundbar to adjust the volume, the Chromecast to pause or play, though that doesn't seem to work when playing DVDs on the PS4, where we use the PS4 remote. CEC can also tell the TV to change inputs, so all I have to do is start casting to the Chromecast and the TV turns on and switches to the right input, turn the PS4 on and ditto, etc...
Music in the bathroom? That's a Google Home. Music in the garage or back patio? That's a Bluetooth Jambox. Though that comes with it's own issues.
Yes, simple is good. But these days I'd call this sort of CEC setup the simpler option. I appreciate the Receiver option, but I'm reluctant to switch away from this setup. I've been wanting to build some kick ass speakers using my woodworking and electronics skills, but I can't bring myself to introduce an amp/receiver to the mix.
Aside: Does anyone know of a CEC controller for embedding into DIY soundbars? They make some that do amp+bluetooth+aux in, but I haven't found one that does HDMI in with CEC.