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Comment by dkarras | Hacker News Reader

Just use a latest generation SSRI. Works for most people, minimal side effects. People take SSRIs for less, really. If you don't have PE though it makes you anorgasmic.

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SSRI's give me ED. Doesn't matter how long I can go if I can't get the show started.

Which one? I was talking about something like citalopram / escitalopram which is very highly selective. Though I know that ED is a possible side effect even for escitalopram.

60mg Dapoxetine, chosen for its extremely short half-life.

Often combined in a single tablet with 100mg of Sildenafil.

Take 1 hour before if possible. The Sildenafil kicks in before the Dapoxetine reaches peak absorption.

Double-blind cross over with placebo confirms a significant effect (~2x duration). You may find you cannot ejaculate at all at that dose, and end up taking half a pill.

Or you take the full dose on occasion and go for as long as your partner desires.

I have the opposite problem unfortunately. I already could go however long I wanted (and sometimes longer) but on an SSRI I can't ejaculate at all (sometimes not even by myself) despite having stronger and easier erections. Otherwise the benefit is there so I'm keeping at it. Do you have something for that too?

I’m not an expert on this, but you might find this interesting;

https://www.issm.info/news/sex-health-headlines/cabergoline-...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822480/

Can you name any of the latest generation SSRI? Would taking them in this case make sense if there is no depression etc.

Not seeking medical advice just want some perspective

MDMA works too, and improves just about everything else about the experience.

I was thinking about this: https://news.ycombinator.com/item?id=22030051

Of course you must consult to a doctor, but I've heard them writing those for PE.

Edit: Also found this: https://www.ncbi.nlm.nih.gov/pubmed/17873675

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