I really hope the launch and deployment of JWST goes smoothly. It's costly, being in development for long time, and almost no way to fix(L2 is far away) if something goes wrong.
Yes, such unique projects are really a case of make or break! To be fair, the rate of success in the past is high enough to make us confident they will succeed again... barring unforeseen or unpredictable circumstances in the mechanical start up?