Let's go in another direction here, away from a lot of the hype and cargo cult. I will suggest IntercoolerJS [1] and TurboLinks [2]. These are simple javascript libraries that let you do much of the slick in-dom updates without all the hassle of build pipelines, JSX, or functional paradigms.
I have deployed this in production for clinical trials applications as well as into side projects. Using this with Django means I have a lean, mean, and simple stack without a complicated build or deployment process.