Economic rent like this pops up even in human-made domains of potentially infinite expanse, such as the internet. There is no limit to the number of domain names which may exist yet some are far more valuable than those which can be claimed for low-to-no cost. Even social media platforms are valued to include the economic rent of their own user communities. For example, even if there came along a social media platform which was better than Facebook in every way, users would still value Facebook more because it has more community and community-generated activity and content.
Same with domain names. People are interested in using shorter domains like abc.com, not long ones such as xyajfbeusnfdbdjak.craptld
The scarcity applies to a grade of land or string, not to all land in the Universe or string space in total.
It is difficult to compare the 'grades' of land, because the grading is not discrete but somewhat continuous.
The hypothetical expansion of the human race in the coming centuries has no bearing on decisions that are made with the next years and decades in mind.