I tried it in the past (maybe a year ago) and just 2 weeks ago, too. The experience I had was aweful. Pretty much nothing was working. Maybe I am too biased from Parcel and I got disappointed when even simple things such as starting with an HTML file as root module does not work, or when importing CSS does not work, or when using TypeScript does not work.
What I particularly disliked is that it cannot even cope with the standard stuff that I throw at it. CommonJS modules (only the standard...)? You need a plugin. Not only that: I had to specify what modules I wanted to include and what they export. Do you know a way around all these wholes or is your solution always pretty much self-contained?