I am a stereotypical backend developer with little experience implementing custom design, before Tailwind I was using stock bootstrap.

I am building my first product using this tool and after I get over first hurdles everything went smoothly. Tutorials on their homepage are pure gold and helped me going. Also take a look on youtube channels of Tailwind authors (Refactoring UI), those are great.

In conclusion I am glad I've taken some time to learn basics, it took me maybe three or four afternoons and now I'm as productive as in Bootstrap + my designs look much much better.