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Comment by idclip | Hacker News Reader

How does one regenerate their micro biome?

At least when it comes to diet: sauerkraut, kefir, vegetables/leafy greens (dirt has good bacteria and some of it always remains on vegetables).

For me, it helps to cut out sugar. I cannot say that I suddenly feel like a new person or anything after a while without sugar, but there is definitely a lift of my my baseline mental stamina, when it comes to handling everyday situations.

Sleep also improves without sugar. That may be the cause also.

Fecal matter transplant.

Prebiotic and probiotic food.

There are no scientific evidence that probiotics work or don't work. It's a 50-50 unproven by science. The ones that prove it are sponsored and none disprove it either. My 50c as a long term IBS patient.

As a mostly controlled IBS patient, I find having a good diet works best. Fruit, veg, whole grains. Avoid sugary soda drinks, caffeine, coffee and too much alcohol. I think all of those things promote good gut bacteria. Prebiotics fall into that category.

Out of curiosity, did you get a microbiome test (e.g. from Viome) before and after removing each one of these elements from your diet, or did you make conclusions based on how you felt? Of course everyone is different, but I think published research supports your suggestion that sugar and alcohol are "bad" and fruits, vegetables, and resistant starch are "good", but disagrees on coffee. Here's a recent study showing association between high coffee intake and "good" gut microbiome [1]. I put good and bad in scare quotes because it seems the science around this is still pretty weak, mostly based on associations rather than clear and verified mechanisms. [1] https://gi.org/media/press-info-scientific-meeting/featured-...

Sorry for the confusion. When I mentioned coffee I was referring to IBS symptoms, not microbiome. Caffeine increases digestive secretions and causes colonic motor activity. Even decaf coffee increases secretions. For a review, see:

https://www.tandfonline.com/doi/abs/10.1080/0036552997500255...

If coffee is causing IBS symptoms (diarrhea), I would imagine that isn't good for your microbiome.

I haven't had any microbiome tests, and it's very difficult to robustly test for the effects of individual foods without doing a placebo controlled trial. However, after removing fizzy HFCS soda drinks, I seem to not have any symptoms that I would associate with an abnormal microbiome in the past year (smelly farts, followed by urgent need to poop, followed by large amount of soft poop after eating, during a period of long-term zero stress). I've made a number of other changes to my diet, such as not drinking tap water, but I suspect HFCS was the main culprit, as the scientific evidence strongly backs that up.

Stress is another main cause of IBS, due to its effects on gut motility.

Damn, are caffeine and coffee associated with bad gut health? Is that anecdotal, or do you know of any research?

Not gut health, but IBS (see my other comment here).

Anecdotally, post antibiotics this winter I had some yogurt and my gut started acting more normal within the day. Not data but definitely seemed to help me.

Alternatively maybe I was already moving past the hump and would have felt better regardless but after antibiotics I’m not sure how I’d get back to a good baseline easier than yogurt or sauerkraut.

It's hard to know without doing a placebo controlled trial. I eat Activia every day, but even I'm not sure it's having any effect and I don't trust Danone's own research. Overall, research seems to be mixed:

https://badgut.org/information-centre/a-z-digestive-topics/p...

Still, I think it's worth using probiotics, as there don't seem to be any negative effects.

Very off topic, but.. did you explain how you recovered from CFS somewhere?

Healthy balanced diet over time, with a side of exercise.

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