The disruption of serotonergic pathways probably isn’t something that can be amended by a serotonergic therapy. I’d actually predict that individuals with Alzheimer’s would experience a diminished effect when taking LSD.
My bias here is more broad. I’m of the belief that the cure to Alzheimer’s is more likely biological than it is chemical. Not overlooking the interoperability of these two things, but rather suggesting that it’s probably a problem that requires a more sophisticated treatment than purely consuming a drug.
That said, I’m very excited to see microdosing being studied and interested in the outcomes of this trial, whatever they may be. Certainly, the results here could tell us something we haven’t yet discovered about LSD or Alzheimer’s, even if there is no therapeutic application in this case.