Except when the Friday deployment breaks production and one of your employees needs to fix the issue on Saturday instead of relaxing with their family.
The biggest extreme that I've faced was a team where there was a 36 hour window between Wednesday and Thursday where deployments to production were allowed and it was a nightmare getting any code out especially with most deployments involving 10-20 new commits so if something did break we had to rollback a lot and rack our heads to figure out what went wrong.
Also, sites "go down" for more reasons than deployments, and often, a deployment is one of the fastest or only ways to fix or work around the issue.